Legal classification of medication
POM and P
Tamsulosin can be obtained in accordance with a prescription (POM) given by an appropriate practitioner and also obtained from pharmacies (P) through a one to one consultation with a pharmacist.
Formulations
Tamsulosin is available as modified preparations of capsules and tablets and only comes in 400mcg (0.4mg) strength.
Class of drug
Tamsulosin is an alpha-1 adrenoceptor antagonist (alpha-1 blocker).
Indications
Tamsulosin is used for the treatment of urinary symptoms of benign prostatic hyperplasia (BPH) in men. Benign prostatic hyperplasia is a progressive enlargement of the prostate gland that leads to lower urinary tract symptoms such as hesitancy, weak stream and urgency. Prostate enlargement puts pressure on the urethra where it passes through the gland, obstructing the flow of urine. In addition the bladder wall may thicken and this loss of elasticity may reduce the volume of urine held by the bladder.
How does it work?
Tamsulosin acts by relaxing the smooth muscle in the prostate that surround the urethra. This relieves pressure on the urethra, allowing urine to flow more freely.
How to take it?
One tablet or capsule is taken after breakfast or the first meal of the day. The capsule is swallowed whole with a glass of water while standing or sitting. The tablet or capsule should not be broken or pulled apart as this may have an effect on the release of the long-acting active ingredient.
Pregnancy and Breast feeding
Tamsulosin is intended for males only.
Contra-indications
Tamsulosin should be avoided in patients with a history of sudden fall in blood pressure when a person stands up (postural hypotension) or temporary loss of consciousness when urinating (micturition syncope).
Side-effects
Side-effects include:
Author: Mr Shiraz Mughal, MPharmS Editor: Dr Shazan Chughtai, MB BS
